Institute for Systems Biology
Using the science of systems biology to predict, prevent and cure disease.
GiveRadar doesn't take a cut. Donate directly on their site.
Make your donationAbout Institute for Systems Biology
Institute for Systems Biology (ISB) is a nonprofit scientific research organization in Seattle. Learn how our science is transforming health.
Verified certifications
Confirmed against the issuing authority - not self-reported.
Mission
Using the science of systems biology to predict, prevent and cure disease.
Focus areas & reach
· What they work on and whereHow it stacks up against peers
· vs. 8 similar science & technology in United StatesConcerns
· None foundWhere every $1 goes
· FY2024 · IRS 990 (FY2024)GiveRadar Analysis
Original analysis from GiveRadar's dataset of comparable organizations
Based on the records currently verified by GiveRadar, Institute for Systems Biology has a complete profile, cross-referenced across 6 independent sources including the IRS.
- GiveRadar has cross-referenced this organization across 6 independent sources, led by the IRS - more than 98% of comparable charities. See the sources
- GiveRadar holds 14 years of financial filings for this organization, the most recent for fiscal year 2024 - a deeper filing history than 97% of the 3,236 science & technology charities in the United States with filings on record. See the filings
- GiveRadar holds a more complete profile for this organization than for 87% of the 7,611 science & technology charities in the United States it tracks, because GiveRadar has verified its financial disclosures and its governance. Most of those have little verified data on record yet. View this cohort
- government registration
- financial records (14 filed years)
- disclosed leadership
- a website
- a donation page
- third-party accreditation
- a contact email
- an owner-submitted profile claim
Analysis based on GiveRadar's benchmark dataset of 2026-07-03. It describes what GiveRadar has verified, not a judgment of the organization itself.
Common questions
· Auto-generated from filings + methodologyInstitute for Systems Biology is a registered science & technology nonprofit based in Renton, WA, United States. It is registered with the Internal Revenue Service (IRS). It was founded in 1999 and has been operating for 27 years. Its EIN is 912003593. According to GiveRadar's records, it holds active tax-deductible status on the IRS Publication 78 list, which means donations are tax-deductible and the organization is in good standing with the IRS. GiveRadar's Integrity Assessment for the organization is 77/100, which reflects how much public information is available, not whether the charity is legitimate. The organization reports $42M in annual revenue. 101 officers and directors are publicly disclosed. No red flags have been detected.
Institute for Systems Biology's EIN (Employer Identification Number) is 912003593. This is the organization's IRS tax identification number; you can use it to verify tax-exempt status and to look up its Form 990 filings with the IRS.
Institute for Systems Biology has a GiveRadar Integrity Assessment of 77/100. This score combines five components: Registration (20 pts), Financial Transparency (30 pts), Governance (20 pts), Contact Availability (10 pts), and Data Recency (20 pts), with negative adjustments for any red flags. A score of 77 ('Strong transparency') reflects well-documented governance, recent financials, named leadership, and working contact details. For comparison, the average integrity assessment for science & technology charities in United States is 90/100.
Institute for Systems Biology is located in Renton, WA, United States. The organization was established in 1999 and has been active for 27 years.
Based on official tax filings, Institute for Systems Biology has $42M in annual revenue. It allocates 71% of expenses to programs and services. This is below the average of 82% for science & technology charities in United States. Its revenue is significantly above the peer average of $15M. Create a free GiveRadar account to view the complete financial breakdown with year-over-year trends.
Institute for Systems Biology is classified as a Science & Technology organization, registered in United States. It operates as a Publicly-supported charity (509(a)(2)). By size, it is categorized as a large organization. It has $42M in annual revenue. The organization has 101 disclosed officers and directors.
No red flags have been detected for Institute for Systems Biology. GiveRadar automatically screens charities for concerning patterns including high executive compensation, low program spending, and missing financial filings. Based on available official data, no issues have been identified.
According to GiveRadar's records, Institute for Systems Biology holds active tax-deductible status on the IRS Publication 78 list, which means donations are tax-deductible and the organization is in good standing with the IRS. It is registered with the Internal Revenue Service (IRS). It reports that 71% of expenses go to programs (the peer average is 82%). You can donate directly through their official donation page linked on their GiveRadar profile. GiveRadar provides data for research and does not endorse any organization. A GiveRadar Integrity Assessment reflects how much public data is available, not whether an organization is safe to donate to, so it is always smart to do your own research before giving.
Institute for Systems Biology (ISB) is a nonprofit scientific research organization in Seattle. Learn how our science is transforming health. Institute for Systems Biology is classified as a science & technology organization registered in United States. The organization was founded in 1999.
Among science & technology charities registered in United States: It allocates 71% of expenses to programs, below the peer average of 82%. Its annual revenue of $42M is well above the peer average of $15M.
Yes, donations to Institute for Systems Biology are generally tax-deductible in the United States. Its EIN is 912003593, which you can use for tax filing purposes. Donors can typically deduct contributions on their federal income tax return if they itemize deductions. Consult a tax professional for guidance specific to your situation.
Filing history
10 years on file from IRS 990 (FY2024): revenue, expenses, program spending, assets, and liabilities by fiscal year.
See 5 years of revenue, expense breakdowns, and balance sheet.
Sign up to viewTaxes
Tax-deductibility for donors
Donations may be tax-deductible for residents of United States under local rules. Confirm with the charity directly.
INSTITUTE FOR SYSTEMS BIOLOGY is registered in United States. Donations from the Netherlands to charities outside the EU/EEA are generally not tax-deductible for Dutch donors unless the charity is listed on the Dutch ANBI register with foreign-recognized status.
Always confirm tax treatment with the charity directly or your tax advisor before donating.
Staff & volunteers
From filings and published profiles
Leadership
From FY2024 filing
Officers & trustees (25)
Source: Public filings
25 officers and trustees on file - free with a GiveRadar account.
Latest news
From global news sources
2 articles found
From news sources and the organization. Shown for transparency; news never affects the integrity score.
Activity timeline
Filings and press mentions, merged
No reviews yet. Be the first to share your experience.
Have you donated or volunteered here?
Share your experience - it takes 30 seconds. Verified reviews help other donors decide.
Sign up to write a reviewCause areas in United States
How many charities work in each area, with this charity's area highlighted.
Most common causes in United States
Causes charities work on most.
Sources and verification
- Registration and legal identity
- Internal Revenue Service (IRS) - Tax Exempt Organization Search
- Financial filings
- IRS Form 990 filings - Fiscal year 2024 most recent on file.
- Officers and trustees
- Internal Revenue Service (IRS) - Tax Exempt Organization Search - 101 disclosed in the public registry.
- News and media coverage
- GDELT Project + Google News
- Supplementary verification
- ProPublica Nonprofit Explorer
- Supplementary verification
- Wikidata structured data
- Supplementary verification
- Charity Navigator
Data freshness
What we know and don't know
Exactly which public data we hold on this charity. Our score reflects transparency, not impact.
-
Financial data · FY2024 on record
-
Named leadership · 101 officers on file
-
Executive pay · Disclosed
-
Government registration · Registered with an official registry
-
Mission statement · Published
-
Official website · On record
-
Headquarters address · On file
-
Direct contact · Email or phone published
-
Tax-deductibility · Verified
-
Founding date · 1999
-
Programs & activitiesNo named programs listed by the charity
Methodology
GiveRadar builds each profile primarily from official government charity registries, supplemented where available by third-party nonprofit databases and news archives, and combines it into a single 0-100 integrity assessment. The exact sources for this charity are listed above. We don't take a cut of any donation, ever.
Read full methodologyAre you the owner or a board member?
If you represent this organization and want to correct or update its data, you can claim this listing to edit details yourself, or email [email protected] with the correct information. We review every request and respond within 30 days.
Report an issue
Tell us what's wrong with this charity's page. We review every report and typically reply within 2 business days.
Report sent
Thanks for flagging this. Our team will review it.
Press Esc to close
Save Institute for Systems Biology?
Create a free GiveRadar account to save charities and track them in your dashboard.
Quick facts about Institute for Systems Biology
- What is Institute for Systems Biology?
- Institute for Systems Biology is a science & technology publicly-supported charity (509(a)(2)) based in Renton, United States. Institute for Systems Biology (ISB) is a nonprofit scientific research organization in Seattle. Learn how our science is transforming health.
- When was Institute for Systems Biology founded?
- Institute for Systems Biology was founded in 1999.
- Who leads Institute for Systems Biology?
- Kathy Scanlan serves as COO/Treasurer.
- Where is Institute for Systems Biology located?
- Headquartered in Renton, WA, United States.
- What is Institute for Systems Biology's annual budget?
- Annual revenue for fiscal year 2024 is approximately $10M-$100M. 71% of expenses go to program services.
- Is Institute for Systems Biology trustworthy?
- Institute for Systems Biology has a GiveRadar Integrity Assessment of 77 out of 100 (Strong transparency). The score reflects public-data transparency: registration, financial disclosure, governance, contact details, and how recently data was refreshed. It does not measure program impact.
- What is Institute for Systems Biology's registration number?
- IRS EIN: 912003593.
- What is Institute for Systems Biology's website?
- https://isbscience.org/